Preheat the air fryer. Set it to 375°F (190°C) for 3–5 minutes. A hot basket helps with browning and keeps the burgers from sticking.
Mix the beef. In a bowl, combine ground beef, BBQ sauce, Worcestershire, salt, pepper, garlic powder, and onion powder.
Mix gently with your hands or a fork until just combined. Do not overwork or the patties will be tough.
Shape the patties. Divide into 4 equal portions. Form 4-inch rounds, about 1/2 inch thick. Press a small dimple in the center of each patty with your thumb to prevent doming.
Prep the basket. Lightly spray the air fryer basket with oil to minimize sticking.
Place patties in a single layer with space between them. Cook in batches if needed.
Air fry the first side. Cook at 375°F (190°C) for 6 minutes. Resist opening the basket too often; consistent heat helps with browning.
Flip and glaze. Flip the patties.
Brush the tops with a thin layer of BBQ sauce for a sweet, sticky finish. Cook for another 3–5 minutes, depending on thickness and your preferred doneness.
Add cheese. In the last 45–60 seconds, place a slice of cheese on each patty. Close the basket to melt.
If your air fryer runs hot, turn off the heat and let the residual warmth finish the melt.
Toast the buns (optional but great). Remove burgers and rest them for 2–3 minutes. Add buns, cut side up, to the basket and air fry at 350°F (175°C) for 1–2 minutes until lightly crisp.
Build your burgers. Spread mayo, mustard, or more BBQ sauce on the buns. Add lettuce and tomato if you like.
Place the patty, then top with onion and pickles. Serve right away while hot and juicy.